Low-temperature formation of pyridine and (iso)quinoline via neutral-neutral reactions

doi:10.1038/s41550-024-02267-y

	Low-temperature formation of pyridine and (iso)quinoline via neutral-neutral reactions
	Yang, Zhenghai 1; He, Chao 1; Goettl, Shane J.1; Mebel, Alexander M.2; Velloso, Paulo F. G.3; Alves, Marcio O.3; Galvao, Breno R. L.3; Loison, Jean-Christophe 4; Hickson, Kevin M.4; Dobrijevic, Michel 5; Li, Xiaohu6,7 ; Kaiser, Ralf I.1
	2024-05-13
Source Publication	NATURE ASTRONOMY
ISSN	2397-3366
Pages	13
Contribution Rank	6
Abstract	Aromatic molecules represent fundamental building blocks in prebiotic chemistry and are contemplated as vital precursors to DNA and RNA nitrogen bases. However, despite the identification of some 300 molecules in extraterrestrial environments, the pathways to pyridine (C5H5N), pyridinyl (C5H4N) and (iso)quinoline (C9H7N)-the simplest representative mono- and bicyclic aromatic molecules carrying nitrogen-are elusive. Here we afford compelling evidence on the gas-phase formation of methylene amidogen (H2CN) and cyanomethyl (H2CCN) radicals via molecular beam studies and electronic structure calculations. The modelling of the chemistries of the Taurus molecular cloud (TMC-1) and Titan's atmosphere contemplates a complex chain of reactions synthesizing pyridine, pyridinyl and (iso)quinoline from H2CN and H2CCN at levels of up to 75%. This study affords unique entry points to precursors of DNA and RNA nitrogen bases in hydrocarbon-rich extraterrestrial environments thus changing the way we think about the origin of prebiotic molecules in our Galaxy. A pathway towards the formation of pyridine and (iso)quinoline, precursors to DNA and RNA, is revealed for conditions appropriate to Saturn's moon Titan and the Taurus molecular cloud, providing insight into the synthesis of prebiotic molecules in space.
DOI	10.1038/s41550-024-02267-y
Indexed By	SCI
Language	英语
WOS Keyword	POLYCYCLIC AROMATIC-HYDROCARBONS ; ATMOSPHERE ; CHEMISTRY ; BENZENE ; TITAN ; IDENTIFICATION ; NUCLEOBASES ; MOLECULES ; DENSITY ; ATOMS
Funding Project	US Department of Energy, Basic Energy Sciences[DE-FG02-03ER15411] ; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)[311508/2021-9] ; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)[405524/2021-8]
WOS Research Area	Astronomy & Astrophysics
WOS Subject	Astronomy & Astrophysics
WOS ID	WOS:001220931600001
Publisher	NATURE PORTFOLIO
Funding Organization	US Department of Energy, Basic Energy Sciences ; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
Citation statistics	Cited Times:2[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.xao.ac.cn/handle/45760611-7/6715
Collection	射电天文研究室_天体化学研究团组
Corresponding Author	Mebel, Alexander M.; Galvao, Breno R. L.; Loison, Jean-Christophe; Li, Xiaohu; Kaiser, Ralf I.
Affiliation	1.Univ Hawaii Manoa, Dept Chem, Honolulu, HI 96822 USA 2.Florida Int Univ, Dept Chem & Biochem, Miami, FL 33199 USA 3.Ctr Fed Educ Tecnol Minas Gerais, CEFET MG, Belo Horizonte, Brazil 4.Univ Bordeaux, Inst Sci Mol, CNRS, Talence, France 5.Univ Bordeaux, Lab Astrophys Bordeaux, CNRS, Pessac, France 6.Chinese Acad Sci, Xinjiang Astron Observ, Urumqi, Peoples R China 7.Chinese Acad Sci, Key Lab Radio Astron, Urumqi, Peoples R China
Corresponding Author Affilication	Xinjiang Astronomical Observatory, Chinese Academy of Sciences
Recommended Citation GB/T 7714	Yang, Zhenghai,He, Chao,Goettl, Shane J.,et al. Low-temperature formation of pyridine and (iso)quinoline via neutral-neutral reactions[J]. NATURE ASTRONOMY,2024:13.
APA	Yang, Zhenghai.,He, Chao.,Goettl, Shane J..,Mebel, Alexander M..,Velloso, Paulo F. G..,...&Kaiser, Ralf I..(2024).Low-temperature formation of pyridine and (iso)quinoline via neutral-neutral reactions.NATURE ASTRONOMY,13.
MLA	Yang, Zhenghai,et al."Low-temperature formation of pyridine and (iso)quinoline via neutral-neutral reactions".NATURE ASTRONOMY (2024):13.

Files in This Item:
File Name/Size	DocType	Version	Access	License
Yang-2024-Low-temper（2949KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	View Application Full Text

File name:	Yang-2024-Low-temperature formation of pyridin.pdf
Format:	Adobe PDF

If you have any objections to this item, please fill out the form below and the administrator will contact you as soon as possible.
Content:
Email：	*
Institution:
Verification Code:	Refresh

Any comments and suggestions are welcomed.
Title:	*
Content:
Email：	*
Verification Code:	Refresh

射电天文研究室知识库